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AdipoGen Life Sciences
anti-DLK1 (mouse), mAb (PF183E)
1: Mouse DLK1 Fc-protein.
2: Human DLK1 Fc-protein.
3: Mouse DLL1 Fc-protein.
4: Mouse DLL4 Fc protein.
5: Mouse Jagged-1 Fc-protein.
6: Unrelated Fc-protein (negative control).
Product Details | |
---|---|
Synonyms | Protein Delta Homolog 1; Fetal Antigen 1; Preadipocyte Factor 1; Pref-1; FA1 |
Product Type | Monoclonal Antibody |
Properties | |
Clone | PF183E |
Isotype | Rat IgG2aκ |
Immunogen/Antigen | Recombinant mouse DLK1 (extracellular domain). |
Application |
ELISA: (direct or indirect: 1:2'000-1:10'000) Note: Tested on recombinant proteins and/or target-protein transfected cell lines in ELISA, Western Blot and/or FACS. |
Crossreactivity | Mouse |
Specificity |
Recognizes mouse DLK1. Does not cross-react with human DLK1. |
Purity Detail | Protein G-affinity purified. |
Concentration | 1mg/ml |
Formulation | Liquid. In PBS. |
Isotype Negative Control | |
Other Product Data |
Uniprot ID: DLK1 (mouse) |
Accession Number | Q09163 |
Shipping and Handling | |
Shipping | BLUE ICE |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice |
After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. |
Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
Documents | |
MSDS | Download PDF |
Product Specification Sheet | |
Datasheet | Download PDF |
The transmembrane and secreted protein delta-like 1 homolog (DLK1; Protein delta homolog 1; Preadipocyte factor 1; Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-α converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.