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AdipoGen Life Sciences
Meteorin-like (mouse) (rec.)
230
CHF
CHF 230.00
In stock
AG-40B-0149-C01010 µgCHF 230.00
AG-40B-0149-30103 x 10 µgCHF 455.00
| Product Details | |
|---|---|
| Synonyms | Interleukin-41; IL-41; IL41; Metrnl; Subfatin; Cometin |
| Product Type | Protein |
| Properties | |
| Source/Host | HEK 293 cells |
| Sequence |
Mouse meteorin-like [IL-41] (46-311) is fused at the N-terminus to a FLAG®-tag. |
| Crossreactivity | Mouse |
| MW | ~35kDa (SDS-PAGE); ~ 40 kDA (Monomer) (SEC) |
| Purity | ≥95% (SDS-PAGE) |
| Endotoxin Content | <0.1EU/μg purified protein (LAL test). |
| Concentration | 0.1mg/ml after reconstitution. |
| Reconstitution | Reconstitute with 100μl sterile water. |
| Formulation | Lyophilized. Contains PBS. |
| Other Product Data |
Uni-Prot link Q8VE43: Meteorin-like (mouse) |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0.1% BSA should be used for further dilutions. |
| Use/Stability |
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
Meteorin-like (interleukin-41; cometin; subfatin) is a potent new neurotrophic factor promoting neurite outgrowth from dorsal root ganglion cells. Meteorin-like is also a novel adipokine expressed by adipose tissue being downregulated upon caloric restriction. Meteorin-like is secreted by muscles during exercise and converts white adipose cells into brown fat tissue.
Product References
- METRNL attenuates lipid-induced inflammation and insulin resistance via AMPK or PPARδ-dependent pathways in skeletal muscle of mice: T.W. Jung, et al.; Exper. Mol. Med. 50, 122 (2018)
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