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AdipoGen Life Sciences
Rubratoxin A
370
CHF
CHF 370.00
In stock
AG-CN2-0092-C250250 µgCHF 370.00
AG-CN2-0092-C500500 µgCHF 660.00
Product Details | |
---|---|
Synonyms | BRN 1633008; HSDB 3532 |
Product Type | Chemical |
Properties | |
Formula |
C26H32O11 |
MW | 520.2 |
CAS | 22467-31-8 |
RTECS | GX9450000 |
Source/Host Chemicals | Isolated from Penicillium sp. |
Purity Chemicals | ≥95% (HPLC) |
Appearance | White powder. |
Solubility | Soluble in DMSO or acetone. Methanol or ethanol are not recommended as solvents, as they esterify Rubratoxin A. |
Declaration | Manufactured by the Institute of Microbial Chemistry (BIKAKEN). |
InChi Key | XOEFANNJIKAWGX-AWYIYDNTSA-N |
Smiles | [H][C@]1(CC=CC(=O)O1)[C@@H](O)[C@@]1([H])CC2=C(C(=O)OC2O)[C@@]([H])([C@H](O)CCCCCC)[C@H](O)C2=C(C1)C(=O)OC2=O |
Shipping and Handling | |
Shipping | BLUE ICE |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | Keep cool and dry. |
Use/Stability | Stable for at least 3 years after receipt when stored at -20°C. |
Documents | |
MSDS | Download PDF |
Product Specification Sheet | |
Datasheet | Download PDF |
Description
- Mycotoxin [1].
- Potent and selective competitive protein phosphatase 2A (PP2A) inhibitor. Does not inhibit PP1, PP2B, PTP1B, ALP and CIP [2].
- Antitumor agent. Antimetastatic [2].
Product References
- The structure of rubratoxin A, a toxic metabolite of Penicillium rebrum: M.O. Moss, et al.; Tetrahedron Lett. 5, 367 (1969)
- Rubratoxin A specifically and potently inhibits protein phosphatase 2A and suppresses cancer metastasis: S. Wada, et al.; Cancer Sci. 101, 743 (2010)