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AdipoGen Life Sciences
Penicillide
75
CHF
CHF 75.00
In stock
AG-CN2-0122-C250250 µgCHF 75.00
AG-CN2-0122-M0011 mgCHF 225.00
| Product Details | |
|---|---|
| Synonyms | Vermixocin A; Antibiotic AS 186A; Antibiotic MC 140 |
| Product Type | Chemical |
| Properties | |
| Formula |
C21H24O6 |
| MW | 372.4 |
| CAS | 55303-92-9 |
| Source/Host Chemicals | Isolated from Penicillium sp. |
| Purity Chemicals | ≥95% (HPLC) |
| Appearance | Off-white solid. |
| Solubility | Soluble in DMSO, ethanol or methanol. |
| InChi Key | UOWGLBYIKHMCIS-UHFFFAOYAA |
| Smiles | COC1=C(C=CC2=C1C(=O)OCC1=C(O2)C(O)=CC(C)=C1)C(O)CC(C)C |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Keep cool and dry. |
| Use/Stability | Stable for at least 3 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Plant growth inhibitor [1]. Mycotoxin.
- Acyl-CoA-cholesterol acyltransferase (ACAT) inhibitor [3, 6].
- Anticancer compound. Cytotoxic [4].
- Non-peptidic oxytocin receptor antagonist [5].
- Calpain inhibitor [7].
Product References
- Structure of penicillide, a new metabolite produced by a Penicillium sp.: T. Sassa, et al.; Tetrahedron Lett. 15, 3941 (1974)
- Penicillide and dehydroisopenicillide from Talaromyces derxii: K. Suzuki, et al.; Phytochemistry 30, 2096 (1991)
- Purpactins, new inhibitors of acyl-CoA:cholesterol acyltransferase produced by Penicillium purpurogenum. III. Chemical modification of purpactin A: H. Nishida, et al.; J. Antibiot. (Tokyo) 44, 152 (1991)
- Vermixocins A and B, two novel metabolites from Penicillium vermiculatum: B. Proksa, et al.; J. Antibiot. (Tokyo) 45, 1268 (1992)
- Potent, non-peptidic oxytocin receptor antagonists from a natural source: G.M. Salituro, et al.; Bioorg. Med. Chem. Lett. 3, 337 (1993)
- AS-186 compounds, new inhibitors of acyl-CoA: cholesterol acyltransferase from Penicillium asperosporum KY1635: K. Kuroda, et al.; J. Antibiot. (Tokyo) 47, 16 (1994)
- Penicillide, a Nonpeptide Calpain Inhibitor, Produced by Penicillium sp. F60760: M.C: Chung, et al.; J. Microbiol. Biotechnol. 8, 188 (1998)
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