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AdipoGen Life Sciences
Bikaverin
80
CHF
CHF 80.00
In stock
AG-CN2-0130-C250250 µgCHF 80.00
AG-CN2-0130-M0011 mgCHF 240.00
| Product Details | |
|---|---|
| Synonyms | NSC 215139; BRN 0358013; Lycopersin; Mycogonin; Passiflorin |
| Product Type | Chemical |
| Properties | |
| Formula |
C20H14O8 |
| MW | 382.3 |
| CAS | 33390-21-5 |
| RTECS | DM2901000 |
| Source/Host Chemicals | Isolated from Fusarium sp. |
| Purity Chemicals | ≥95% (TLC) |
| Appearance | Dark red solid. |
| Solubility | Soluble in DMSO. |
| InChi Key | ZOQMSOSJEWBMHP-UHFFFAOYSA-N |
| Smiles | COC1=CC(C)=C2C(=O)C3=C(OC2=C1)C(O)=C1C(=O)C(OC)=CC(=O)C1=C3O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Keep cool and dry. |
| Use/Stability | Stable for at least 3 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Antibiotic [1].
- Antiprotozoal [1].
- Antifungal [2].
- Anticancer [3-7].
- ATP synthesis inhibitior [3, 4].
- Haemolytic agent [5].
- Antioomycete [8].
- Spermidine-induced autoactivation inhibitor [9].
- Plasma hyaluronan-binding protein (PHBP) inhibitor (active form) [9].
- Review [10].
Product References
- Bikaverin, an antibiotic from ibberella fujikoi, effective against Leishmania brasiliensis: J. Balan, et al.; Folia Microbiol. 15, 479 (1970)
- Isolation and characterization of a fungal vacuolation factor (bikaverin): J.W. Cornforth, et al.; J. Chem. Soc. Perkin 16, 2786 (1971)
- New potential cytotoxic and antitumor substances I. In vitro effect of bikaverin and its derivatives on cells of certain tumors: J. Fuska, et al.; Neoplasma 22, 335 (1975)
- Effects of bikaverin on purine nucleotide synthesis and catabolism in Ehrlich ascites tumor cells in vitro: J.F. Henderson, et al.; Biochem. Pharmacol. 26, 1973 (1977)
- Inhibition of mitochondrial functions by the antibiotics, bikaverin and duclauxine: L. Kovac, et al.; J. Antibiot. (Tokyo) 31, 616 (1978)
- Effects of selected secondary metabolites of Fusarium moniliforme on unscheduled synthesis of DNA by rat primary hepatocytes: W.P. Norred, et al.; Food Chem. Toxicol. 30, 233 (1992)
- Search for cell motility and angiogenesis inhibitors with potential anticancer activity: beauvericin and other constituents of two endophytic strains of Fusarium oxysporum: J. Zhan, et al.; J. Nat. Prod. 70, 227 (2007)
- Bikaverin and fusaric acid from Fusarium oxysporum show antioomycete activity against Phytophthora infestans: S.W. Son, et al.; J. Appl. Microbiol. 104, 692 (2008)
- Purpurin as a specific inhibitor of spermidine-induced autoactivation of the protease plasma hyaluronan-binding protein: N. Nishimura, et al.; Biol. Pharm. Bull. 33, 1430 (2010)
- Bikaverin production and applications: M.C. Limon, et al.; Appl. Microbiol. Biotechnol. 87, 21 (2010) (Review)
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