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AdipoGen Life Sciences
Fuscin
220
CHF
CHF 220.00
In stock
AG-CN2-0138-M0011 mgCHF 220.00
AG-CN2-0138-MM252.5 mgCHF 460.00
| Product Details | |
|---|---|
| Synonyms | 3,4,7,9-Tetrahydroxy-6-methyl-1H-phenalen-1-one |
| Product Type | Chemical |
| Properties | |
| Formula |
C15H16O5 |
| MW | 276.3 |
| CAS | 83-85-2 |
| Source/Host Chemicals | Isolated from Oidiodendron sp. |
| Purity Chemicals | ≥95% (HPLC) |
| Appearance | Brown solid. |
| Solubility | Soluble in DMSO. Insoluble in water. |
| InChi Key | OSJKAGRXDVEZQO-UHFFFAOYSA-N |
| Smiles | CC1OC(=O)C=C2C3=C(OC(C)(C)CC3)C(=O)C(O)=C12 |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Keep cool and dry. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Mycotoxin.
- Antibacterial agent.
- ADP transport inhibitor.
- NADH dehydrogenase (NADH-Coenzyme Q oxidoreductase; Complex I) inhibitor. Inhibits mitochondrial respiration and oxidative phosphorylation (OXPHOS).
- Human CCR5 receptor antagonist.
- Anti-HIV compound.
Product References
- Fuscin, an antibacterial pigment from Oidiodendron fuscum Robak: S.E. Michael; Biochem. J. 1948, 42 (1948)
- Fuscin, an Inhibitor of NADH Dehydrogenase: P.M. Vignais; Inhibitors Tools in Cell Research 20, 274 (1969)
- Fuscin, an inhibitor of respiration and oxidative phosphorylation in ox-neck muscle mitochondria: K.S. Cheah; Biochim. Biophys. Acta 275, 1 (1972)
- Fuscin, an inhibitor of mitochondrial SH-dependent transport-linked functions: P.M. Vignais & P.V. Vignais; Biochim. Biophys. Acta 325, 357 (1973)
- 10-Methoxydihydrofuscin, fuscinarin, and fuscin, novel antagonists of the human CCR5 receptor from Oidiodendron griseum: K. Yoganathan, et al.; J. Nat. Prod. 66, 1116 (2003)
- Macrophages Promote Ovarian Cancer-Mesothelial Cell Adhesion by Upregulation of ITGA2 and VEGFC in Mesothelial Cells: S-K. Cho, et al.; Cells 12, 384 (2023)
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