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AdipoGen Life Sciences
Neoxaline
240
CHF
CHF 240.00
In stock
AG-CN2-0154-M0011 mgCHF 240.00
AG-CN2-0154-M0055 mgCHF 960.00
| Product Details | |
|---|---|
| Synonyms | Nedoxaline; BRN 5669473 |
| Product Type | Chemical |
| Properties | |
| Formula |
C23H25N5O4 |
| MW | 435.5 |
| CAS | 71812-10-7 |
| RTECS | NJ5835000 |
| Source/Host Chemicals | Isolated from Aspergillus japonicus Fg-551. |
| Purity Chemicals | ≥97% (HPLC) |
| Appearance | White solid. |
| Solubility | Soluble in methanol, chloroform or ethyl acetate. Insoluble in water or hexane. |
| InChi Key | HHLNXXASUKFCCX-LICLKQGHSA-N |
| Smiles | CON1C2=C(C=CC=C2)C2(CC(O)C(=O)N3\C(=C\C4=CNC=N4)C(=O)NC123)C(C)(C)C=C |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
Protect from light. Protect from moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Antimitotic. Cell cycle inhibitor at the G2/M phase [3, 4].
- Antiproliferative [3].
- Weak CNS stimulant with weak inhibitory activity on blood platelet aggregation [1, 2].
- Mycotoxin [1].
Product References
- Neoxaline, a new alkaloid produced by Aspergillus japonicus. Production, isolation and properties: A. Hirano, et al.; J. Antibiot. 32, 781 (1979)
- Oxaline and Neoxaline: Y. Konda, et al.; Chem. Pharm. Bull. 28, 2987 (1980)
- Oxaline, a fungal alkaloid, arrests the cell cycle in M phase by inhibition of tubulin polymerization.: Y. Koizumi, et al.; Biochim. Biophys. Acta 1693, 47 (2004)
- Efficient total synthesis of novel bioactive microbial metabolites: T. Sunazuka, et al.; Acc. Chem. Res. 41, 302 (2008)
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