anti-CD357 [GITR] (human), mAb (ANC7D6) (FITC)

CHF 352.00
In stock
ANC-268-040120 testsCHF 352.00
More Information
Product Details
Synonyms GITR; Glucocorticoid-induced TNF Receptor; AITR; Activation-inducible TNF-related; TNFRSF18
Product Type Monoclonal Antibody
Properties
Clone ANC7D6
Isotype Mouse IgMκ
Immunogen/Antigen Recombinant human GITR, PHA stimulated human PBL.
Label/Conjugates FITC
Application

Flow Cytometry
ELISA

Crossreactivity Human
Formulation 50 mM Sodium Phosphate pH 7.5, 500 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative).
Isotype Negative Control

Mouse IgM Isotype Control (FITC)

Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by Ancell Corporation.
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability Stable for at least 1 year after receipt when stored at +4°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

Glucocorticoid induced TNF receptor family related gene (GITR; AITR) is a type 1 228 amino acid transmembrane protein that has been designated TNFRSF18. GITR is expressed mainly by CD4+ CD25+ T lymphocytes. Its engagement by antibodies or its ligand (GITRL) induces a costimulatory signal which can break T cell suppression. GITR has been implicated as a regulatory mechanism in anti-parasitic immune resposes, and is involved with macrophages activation in atherosclerotic plaque formation.

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