anti-CD357 [GITR] (human), mAb (ANC5E3) (FITC)

CHF 423.00
In stock
ANC-368-040120 testsCHF 423.00
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Product Details
Synonyms GITR; Glucocorticoid-induced TNF Receptor; AITR; Activation-inducible TNF-related; Tumor Necrosis Factor Receptor Superfamily Member 18; TNFRSF18
Product Type Monoclonal Antibody
Clone ANC5E3
Isotype Mouse IgG3κ
Immunogen/Antigen Recombinant human GITR, PHA stimulated human PBL.
Label/Conjugates FITC

Flow Cytometry

Crossreactivity Human
Formulation 50 mM Sodium Phosphate pH 7.5, 500 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative).
Isotype Negative Control

Mouse IgG3 Isotype Control (FITC)

Other Product Data

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Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by Ancell Corporation.
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability Stable for at least 1 year after receipt when stored at +4°C.
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Product Specification Sheet
Datasheet Download PDF

Glucocorticoid induced TNF receptor family related gene (GITR; AITR) is a type 1 228 amino acid transmembrane protein that has been designated TNFRSF18. GITR is expressed mainly by CD4+ CD25+ T lymphocytes. Its engagement by antibodies or its ligand (GITRL) induces a costimulatory signal which can break T cell suppression. GITR has been implicated as a regulatory mechanism in anti-parasitic immune resposes, and is involved with macrophages activation in atherosclerotic plaque formation.

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