Ancell

anti-CD273 [B7-DC/PD-L2] (human), mAb (ANC8D12) (Biotin)

CHF 423.00

In stock

ANC-273-030100 µgCHF 423.00

More Information
Product Details
Synonyms	Programmed Death Ligand 2
Product Type	Monoclonal Antibody
Properties
Clone	ANC8D12
Isotype	Mouse IgG2aκ
Immunogen/Antigen	Recombinant human CD273.
Label/Conjugates	Biotin
Application	FACS ELISA Functional Application: Blocking
Crossreactivity	Human
Purity	≥95% (SDS-PAGE)
Formulation	50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative).
Isotype Negative Control	Mouse IgG2a Isotype Control (Biotin)
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
Declaration	Manufactured by Ancell Corporation.
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	+4°C
Handling Advice	Avoid freeze/thaw cycles.
Use/Stability	Stable for at least 1 year after receipt when stored at +4°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

CD273 (B7-DC; PD-L2) is a type I surface molecule with homology to CD80, CD86, CD274. It is expressed primarily by dendritic cells and provides a stimulatory signal to CD279 (PD-1; Programmed Cell Death 1) which has an important immunoregulatory role by downregulating the T cell response. CD273 binds to CD279 (PD-1) with a 2-6 fold higher affinity than CD274 and is an important component of immune regulation.

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