anti-CD273 [B7-DC/PD-L2] (human), mAb (ANC8D12) (preservative free)
|Synonyms||Programmed Death Ligand 2|
|Product Type||Monoclonal Antibody|
|Immunogen/Antigen||Recombinant human CD273.|
|Formulation||50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl.|
|Isotype Negative Control|
|Other Product Data||
Click here for Original Manufacturer Product Datasheet
|Declaration||Manufactured by Ancell Corporation.|
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||+4°C|
Avoid freeze/thaw cycles.
|Use/Stability||Stable for at least 1 year after receipt when stored at +4°C.|
|Product Specification Sheet|
CD273 (B7-DC; PD-L2) is a type I surface molecule with homology to CD80, CD86, CD274. It is expressed primarily by dendritic cells and provides a stimulatory signal to CD279 (PD-1; Programmed Cell Death 1) which has an important immunoregulatory role by downregulating the T cell response. CD273 binds to CD279 (PD-1) with a 2-6 fold higher affinity than CD274 and is an important component of immune regulation.