anti-CD273 [B7-DC/PD-L2] (human), mAb (ANC8D12) (FITC)

CHF 352.00
In stock
ANC-273-040120 testsCHF 352.00
More Information
Product Details
Synonyms Programmed Death Ligand 2
Product Type Monoclonal Antibody
Properties
Clone ANC8D12
Isotype Mouse IgG2aκ
Immunogen/Antigen Recombinant human CD273.
Label/Conjugates FITC
Application

FACS
ELISA
Functional Application: Blocking

Crossreactivity Human
Purity ≥95% (SDS-PAGE)
Formulation 50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative).
Isotype Negative Control

Mouse IgG2a Isotype Control (FITC)

Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by Ancell Corporation.
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability Stable for at least 1 year after receipt when stored at +4°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

CD273 (B7-DC; PD-L2) is a type I surface molecule with homology to CD80, CD86, CD274. It is expressed primarily by dendritic cells and provides a stimulatory signal to CD279 (PD-1; Programmed Cell Death 1) which has an important immunoregulatory role by downregulating the T cell response. CD273 binds to CD279 (PD-1) with a 2-6 fold higher affinity than CD274 and is an important component of immune regulation.

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