BellBrook

Enzolution™ PARG Assay System

CHF 0.00
In stock
BBL-3033-1K1000 assaysCHF 1'227.00
BBL-3033-10K10000 assaysCHF 5'072.00
BBL-3033-100K10 x 10000 assaysINQ
More Information
Product Details
Synonyms Poly(ADP-ribose) Glycohydrolase
Product Type Kit
Properties
Application Set Compound Screening
Crossreactivity Human
Quantity

1000 assays/384wells (BBL-3033-1K)

10000 assays/384wells (BBL-3033-10K)

100000 assays/384wells (BBL-3033-100K)

Note: The exact number of assays depends on enzyme reaction conditions.

Detection Type Fluorescent polarization
Kit Contains

- PARG (human) (rec.) (His)
- polyADPR
- Enzyme Assay Buffer B 10X
- 384-Well Low Volume Black Assay Plates (Corning#4514; sold under #BBL-2229 or BBL-2230)

Other Product Data

Click here for Complete Information from the Original Manufacturer
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by BellBrook Labs.
Accession Number Q86W56
Shipping and Handling
Shipping DRY ICE
Short Term Storage -20°C
Long Term Storage -20°C
Handling Advice Avoid freeze/thaw cycles.
Documents
Manual Download PDF
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF
Description

PARG plays an important role in DNA damage repair and has been seen as a potential target for anticancer therapy. The PARG Assay System, when used with the Transcreener ADPR Assay Kit, provides all reagents required to screen and profile PARG modulators.

The PARG Assay System includes PARG (poly (ADP-ribose) glycohydrolase) enzyme, polyADPR, assay plates, and buffers required for a PARG reaction to produce ADPR. The Transcreener ADPR Assay (sold separately) uses coupling enzyme to convert ADPR to AMP, which is detected using far-red tracers that minimize interference. The Transcreener ADPR assay is designed for HTS, Hit-to-Lead, SAR, and general discovery.

The Transcreener ADPR Assay is not included in the assay system but is available for separate purchases.

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