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BellBrook
PARG Assay System
CHF 0.00
In stock
BBL-3033-1K1000 assaysCHF 1'227.00
BBL-3033-10K10000 assaysCHF 5'072.00
BBL-3033-100K10 x 10000 assaysINQ
Figure 1: Schematic Overview of the PARG Assay System with the Transcreener® ADPR FP Assay
| Product Details | |
|---|---|
| Synonyms | Poly(ADP-ribose) Glycohydrolase |
| Product Type | Kit |
| Properties | |
| Application Set | Compound Screening |
| Crossreactivity | Human |
| Quantity |
1000 assays/384wells (BBL-3033-1K) 10000 assays/384wells (BBL-3033-10K) 100000 assays/384wells (BBL-3033-100K) Note: The exact number of assays depends on enzyme reaction conditions. |
| Detection Type | Fluorescent polarization |
| Kit Contains |
- PARG (human) (rec.) (His) |
| Other Product Data |
Click here for Complete Information from the Original Manufacturer |
| Declaration | Manufactured by BellBrook Labs. |
| Accession Number | Q86W56 |
| Shipping and Handling | |
| Shipping | DRY ICE |
| Short Term Storage | -20°C |
| Long Term Storage | -20°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Documents | |
| Manual |
 Download PDF |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
PARG plays an important role in DNA damage repair and has been seen as a potential target for anticancer therapy. The PARG Assay System, when used with the Transcreener ADPR Assay Kit, provides all reagents required to screen and profile PARG modulators.
The PARG Assay System includes PARG (poly (ADP-ribose) glycohydrolase) enzyme, polyADPR, assay plates, and buffers required for a PARG reaction to produce ADPR. The Transcreener ADPR Assay (sold separately) uses coupling enzyme to convert ADPR to AMP, which is detected using far-red tracers that minimize interference. The Transcreener ADPR assay is designed for HTS, Hit-to-Lead, SAR, and general discovery.
The Transcreener ADPR Assay is not included in the assay system but is available for separate purchases.
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