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BioViotica
Rubiginone A2
170
CHF
CHF 170.00
In stock
BVT-0023-M0011 mgCHF 170.00
BVT-0023-M0055 mgCHF 670.00
| Product Details | |
|---|---|
| Synonyms | Fujianmycin B; SNA 8073A |
| Product Type | Chemical |
| Properties | |
| Formula |
C20H16O5 |
| MW | 336.3 |
| CAS | 96695-58-8 |
| Source/Host Chemicals | Isolated from Streptomyces sp. (strain Gö N1/5). |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | Yellow solid. |
| Solubility | Soluble in DMSO or acetone; slightly soluble in methanol. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | MUNUJAJWLPOQBH-LZVRBXCZSA-N |
| Smiles | COC1=CC=CC2=C1C(=O)C1=C(C2=O)C2=C(C=C1)[C@@H](O)[C@H](C)CC2=O |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light. |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. Store solutions at -20°C in the dark. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Antibiotic.
- Antibacterial.
- Stereoisomer of SNA 8073B which is a prolyl endopeptidase (PEP) inhibitor.
- Vincristine-induced cytotoxicity potentiating activity against multi-drug-resistant tumor cells.
Product References
- Fujianmycins A and B, new benz[a]anthraquinone antibiotics from a Streptomyces species: R.W. Rickards & J.P. Wu; J. Antibiot. 38, 513 (1985)
- Chemical and biological properties of rubiginone, a complex of new antibiotics with vincristine-cytotoxicity potentiating activity: M. Oka, et al.; J. Antibiot. 43, 967 (1990)
- SNA-8073-B, a new isotetracenone antibiotic inhibits prolyl endopeptidase. I. Fermentation, isolation and biological properties: K. Kimura, et al.; J. Antibiot. 50, 291 (1997)
- Prolyl endopeptidase inhibitors derived from actinomycetes: K. Kimura, et al.; Biosci. Biotechnol. Biochem. 61, 1754 (1997)
- New biologically active rubiginones from Streptomyces sp.: C. Puder, et al.; J. Antibiot. 53, 329 (2000)
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