CHF 155.00
In stock
BVT-0028-M0011 mgCHF 155.00
BVT-0028-M0055 mgCHF 470.00
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Product Details
Product Type Chemical


MW 420.4
CAS 808750-39-2
Source/Host Chemicals Isolated from Streptomyces bottropensis.
Purity Chemicals ≥98% (HPLC)
Appearance White to off-white solid.
Solubility Soluble in DMSO or methanol.
Identity Determined by 1H-NMR.
Declaration Manufactured by BioViotica.
Smiles CO[C@H]1C2=C(OC)C=CC=C2C(=O)[C@@]23O[C@@]12[C@@H](O)[C@@](O)([C@@H](C)[C@H]3O)C(=O)[C@@H]1O[C@H]1C
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
After reconstitution protect from light at -20°C.
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
  • Antibiotic. Cytotoxic.
  • Antitumor compound. Anti-melanoma drug lead compound. Effective in BRAF V600E mutation cell lines.
  • Potently induces apoptosis in melanoma cells. Localizes to mitochondria, affects energy metabolism in mitochondria rapidly and activates caspase-3/7-dependent apoptotic pathways.
  • Inhibits cell growth in a borad range of human cancer cell lines. Shows cell type specificity inducing strong cytostasis most effective in cancer types with low oxygen respiration ratios like melanomas.
Product References
  1. Towards a total synthesis of the new anticancer agent mensacarcin: synthesis of the carbocyclic core: L.F. Tietze, et al.; Chemistry 10, 5233 (2004)
  2. Cloning and heterologous expression of three type II pks gene clusters from Streptomyces bottropensis: X. Yan, et al.; ChemBioChem 13, 224 (2012)
  3. Insights into the Bioactivity of Mensacarcin and Epoxide Formation by MsnO8: S. Maier, et al.; ChemBioChem 15, 749 (2014)
  4. Functional Characterization of Different ORFs Including Luciferase-Like Monooxygenase Genes from the Mensacarcin Gene Cluster: S. Maier, et al.; ChemBioChem 16, 1175 (2015)
  5. The natural product mensacarcin induces mitochondrial toxicity and apoptosis in melanoma cells: B. Plitzko, et al.; J. Biol. Chem. 292, 21102 (2017)
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