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BioViotica
Aranciamycin
155
CHF
CHF 155.00
In stock
BVT-0364-C500500 µgCHF 155.00
BVT-0364-M0011 mgCHF 265.00
| Product Details | |
|---|---|
| Product Type | Chemical |
| Properties | |
| Formula |
C27H28O12 |
| MW | 544.5 |
| CAS | 72389-06-1 |
| Source/Host Chemicals | Isolated from Streptomyces echinatus. |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | Yellow to orange solid. |
| Solubility | Soluble in DMSO. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | PGCZNTNNZCKKFG-XXHKFMCWSA-N |
| Smiles | [H][C@@]1(O[C@H]2[C@H](OC)[C@](C)(O)C(=O)C3=C2C(O)=C2C(=O)C4=C(C=CC=C4O)C(=O)C2=C3)O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]1OC |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
Description
- Antibiotic.
- Similar to steffimycin.
- Active against Gram-positive bacteria.
- Clostridium histolyticum collagenase inhibitor.
- Antitumor compound.
Product References
- Aranciamycin: W. Keller-Schierlein, et al.; Helv. Chim. Acta 53, 779 (1970)
- Inhibition of collagenase by aranciamycin and aranciamycin derivatives: M. Bols, et al.; J. Med. Chem. 35, 2768 (1992)
- Structure of the anthracycline antibiotic aranciamycin: K. Schmidt-Bäse, et al.; Acta Cryst. C 49, 250 (1993)
- Cloning and heterologous expression of the aranciamycin biosynthetic gene cluster revealed a new flexible glycosyltransferase: A. Luzhetskyy, et al.; ChemBioChem 8, 599 (2007)
- Aranciamycin analogs generated by combinatorial biosynthesis show improved antitumor activity: A. Luzhetskyy, et al.; Appl. Microbiol. Biotechnol. 80, 15 (2008).
- Aranciamycin anhydride, a new anthracycline-type antibiotic isolated from Streptomyces sp. Tü 6384: J. Nachtigall, et al.; J. Antibiot. 63, 397 (2010)
- Aranciamycins I and J, Antimycobacterial Anthracyclines from an Australian Marine-Derived Streptomyces sp.: Z.G. Khalil, et al.; J. Nat. Prod. 78, 949 (2015)
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