R-BAIBA

CHF 191.00
In stock
CDX-A0148-M100100 mgCHF 191.00
CDX-A0148-M500500 mgCHF 574.00
More Information
Product Details
Synonyms D-3-Amino-isobutyric acid
Product Type Chemical
Properties
Formula C4H9NO2
MW 103.12
CAS 2140-95-6
Source/Host Chemicals Synthetic
Purity Chemicals ≥99% (TLC)
Appearance White powder.
Solubility Soluble in methanol or water.
Identity Determined by NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key QCHPKSFMDHPSNR-GSVOUGTGSA-N
Smiles C[C@H](CN)C(O)=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

Beta-Aminoisobutyric acid is a non-protein amino acid originating from the catabolism of thymine and valine. beta-Aminoisobutyric acid occurs in two isomeric forms and both enantiomers of beta-Aminoisobutyric acid can be detected in human urine and plasma. In plasma, the S-enantiomer is the predominant type due to active renal reabsorption. In contrast, urine almost exclusively contains the R-enantiomer of beta-Aminoisobutyric acid, which is eliminated both by filtration and tubular secretion. The S-enantiomer of beta-Aminoisobutyric acid is predominantly derived from the catabolism of valine, the R-enantiomer is the product of the catabolism of the pyrimidine bases uracil and thymine by the enzyme dihydropyrimidine dehydrogenase (DPD), in what constitutes the first step of the pyrimidine degradation pathway. Transient high levels of beta-Aminoisobutyric acid have been observed under a variety of pathological conditions such as lead poisoning, starvation, in total body irradiation and in a number of malignancies. Recently R-/S-enantiomer mixtures have been shown to be browning inducer of white adipose tissue.

Product References

(1) S. Landaas & E. Solem; Scand. J. Clin. Lab. Invest. 43, 95 (1983) | (2) F. Podebrad, et al.; Clin. Chim. Acta 292, 93 (2000) | (3) A.B. Van Kuilenburg, et al.; Biochem. J. 379, 119 (2004)

Quantification of aminobutyric acids and their clinical applications as biomarkers for osteoporosis: Z. Wang, et al., Commun. Biol. 3, 837 (2020)

© 2017 Adipogen Life Sciences. Pictures: © 2012 Martin Oeggerli. All Rights Reserved.