Chemodex

S-BAIBA

CHF 204.00
In stock
CDX-A0147-M100100 mgCHF 204.00
CDX-A0147-M500500 mgCHF 611.00
More Information
Product Details
Synonyms L-3-Amino-isobutyric acid, L-BAIBA
Product Type Chemical
Properties
Formula

C4H9NO2

MW 103.12
CAS 4249-19-8
Source/Host Chemicals Synthetic
Purity Chemicals ≥99% (TLC)
Appearance White to off-white powder
Solubility Soluble in methanol or water.
Identity Determined by NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key QCHPKSFMDHPSNR-VKHMYHEASA-N
Smiles C[C@@H](CN)C(O)=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description

Beta-Aminoisobutyric acid is a non-protein amino acid originating from the catabolism of thymine and valine. beta-Aminoisobutyric acid occurs in two isomeric forms and both enantiomers of beta-Aminoisobutyric acid can be detected in human urine and plasma. In plasma, the S-enantiomer is the predominant type due to active renal reabsorption. In contrast, urine almost exclusively contains the R-enantiomer of beta-Aminoisobutyric acid, which is eliminated both by filtration and tubular secretion. The S-enantiomer of beta-Aminoisobutyric acid is predominantly derived from the catabolism of valine, the R-enantiomer is the product of the catabolism of the pyrimidine bases uracil and thymine by the enzyme dihydropyrimidine dehydrogenase (DPD), in what constitutes the first step of the pyrimidine degradation pathway. Transient high levels of beta-Aminoisobutyric acid have been observed under a variety of pathological conditions such as lead poisoning, starvation, in total body irradiation and in a number of malignancies. Recently R-/S-enantiomer mixtures have been shown to be browning inducer of white adipose tissue. Bone-protective factor.

Product References

(1) S. Landaas & E. Solem; Scand. J. Clin. Lab. Invest. 43, 95 (1983) | (2) F. Podebrad, et al.; Clin. Chim. Acta 292, 93 (2000) | (3) A.B. Van Kuilenburg, et al.; Biochem. J. 379, 119 (2004) | (4) Y. Kitase, et al.; Cell Rep. 22, 1531 (2018) | (5) Z. Wang, et al., Commun. Biol. 3, 837 (2020) | (6) K. Awad, et al.; Int. J. Mol. Sci. 22, 497 (2021) | Ch. Lyssikatos, et al. Res. Square doi.org/10.21203/rs.3.rs-2492688/v1 (2023)

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