Chemodex

DL-3-Hydroxyisobutyric acid sodium salt

CHF 95.00

In stock

CDX-H0085-M250250 mgCHF 95.00

CDX-H0085-G0011 gCHF 285.00

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Product Details
Synonyms	(±)-Sodium β-hydroxyisobutyrate; (±)-β-HIBA-Na; 3-Hydroxy-2-methylpropionic acid sodium salt; Sodium 3-hydroxy-2-methylpropionate
Product Type	Chemical
Properties
Formula	C₄H₇NaO₃
MW	126.09
CAS	1219589-99-7
Source/Host Chemicals	Synthetic
Purity Chemicals	≥96% (GC)
Appearance	White to off-white powder.
Solubility	Soluble in water (50mg/ml). Soluble in DMSO (5mg/ml, ultrasonication needed).
Identity	Determined by NMR.
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	RBJZIQZDAZLXEK-UHFFFAOYSA-M
Smiles	CC(CO)C(=O)O[Na]
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Keep cool and dry. Protect from light and moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

Intermediate formed in the valine catabolism. It is a reactant of the enzymes involved in branched chain amino acid metabolism 3-hydroxyisobutyrate dehydrogenase and 3-hydroxyisobutyryl-CoA hydrolase and it was found to have increased concentrations in MS patient metabolic profiles. This compound may be used to study the distribution, characterization and kinetics of these enzymes. Shown to inhibit key enzymes of the energy metabolism.

Product References

(1) S. Landaas; Clin. Chim. Acta 64, 143 (1975) | (2) J.W. Hawes, et al.; Methods Enzymol. 324, 218 (2000) | (3) F.J. Loupatty, et al.; Am. J. Hum. Genet. 80, 195 (2007) | (4) C.M. Viegas, et al.; Int. J. Dev. Neurosci. 26, 293 (2008) | (5) R.J. Wanders, et al.; J. Inherit. Metab. Dis. 35, 5 (2012)

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