DL-3-Hydroxyisobutyric acid sodium salt

CHF 95.00
In stock
CDX-H0085-M250250 mgCHF 95.00
CDX-H0085-G0011 gCHF 285.00
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Product Details
Synonyms (±)-Sodium β-hydroxyisobutyrate; (±)-β-HIBA-Na; 3-Hydroxy-2-methylpropionic acid sodium salt; Sodium 3-hydroxy-2-methylpropionate
Product Type Chemical


MW 126.09
CAS 1219589-99-7
Source/Host Chemicals Synthetic
Purity Chemicals ≥96% (GC)
Appearance White to off-white powder.
Solubility Soluble in water (50mg/ml). Soluble in DMSO (5mg/ml, ultrasonication needed).
Identity Determined by NMR.
Declaration Manufactured by Chemodex.
Other Product Data

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Our product description may differ slightly from the original manufacturers product datasheet.

Smiles CC(CO)C(=O)O[Na]
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

Intermediate formed in the valine catabolism. It is a reactant of the enzymes involved in branched chain amino acid metabolism 3-hydroxyisobutyrate dehydrogenase and 3-hydroxyisobutyryl-CoA hydrolase and it was found to have increased concentrations in MS patient metabolic profiles. This compound may be used to study the distribution, characterization and kinetics of these enzymes. Shown to inhibit key enzymes of the energy metabolism.

Product References

(1) S. Landaas; Clin. Chim. Acta 64, 143 (1975) | (2) J.W. Hawes, et al.; Methods Enzymol. 324, 218 (2000) | (3) F.J. Loupatty, et al.; Am. J. Hum. Genet. 80, 195 (2007) | (4) C.M. Viegas, et al.; Int. J. Dev. Neurosci. 26, 293 (2008) | (5) R.J. Wanders, et al.; J. Inherit. Metab. Dis. 35, 5 (2012)

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