6-CFDA

CHF 69.00
In stock
CDX-C0040-M02525 mgCHF 69.00
CDX-C0040-M100100 mgCHF 194.00
CDX-C0040-G0011 gCHF 1'418.00
More Information
Product Details
Synonyms 6-Carboxyfluorescein diacetate
Product Type Chemical
Properties
Formula C25H16O9
MW 460.39
CAS 3348-03-6
Source/Host Chemicals Synthetic.
Purity Chemicals ≥95% (HPLC)
Appearance White to yellow powder.
Solubility Soluble in DMSO.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key QMOGCCYGOPYYNT-UHFFFAOYSA-N
Smiles CC(=O)OC1=CC2=C(C=C1)C1(OC(=O)C3=C1C=C(C=C3)C(O)=O)C1=CC=C(OC(C)=O)C=C1O2
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at +4°C.
Documents
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Product Specification Sheet
Datasheet Download PDF

Used to differentiate viable cells from apoptotic cells. Live cells that are not apoptotic accumulate 6-carboxyfluorescein but do not accumulate annexin. CFDA enter cells and are hydrolysed more slowly than FDA. CFDA and FDA hydrolyses obey Michaelis-Menten kinetics with Km values of around 19 and 2 microM, respectively.

Product References

(1) C. Dive et al.; Mol. Cell. Probes 2, 131 (1998) | (2) N. Yamaguchi et al.; J. Appl. Microbiol. 83, 43 (1997) | (3) P.J. Oefner et al.; Anal. Biochem. 223, 39 (1994)

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