5(6)-CFDA

CHF 48.00
In stock
CDX-C0046-M02525 mgCHF 48.00
CDX-C0046-M100100 mgCHF 153.00
CDX-C0046-G0011 gCHF 997.00
More Information
Product Details
Synonyms 5(6)-Carboxyfluorescein diacetate
Product Type Chemical
Properties
Formula C25H16O9
MW 460.39
CAS 124387-19-5
Source/Host Chemicals Synthetic.
Purity Chemicals ≥90% (HPLC)
Appearance White powder.
Solubility Soluble in DMSO.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key DCPDRLHHNBUQPJ-UHFFFAOYSA-N
Smiles CC(O)=O.CC(=O)OC1=CC2=C(C=C1)C1(OC(=O)C3=C1C=CC=C3)C1=CC=C(OC(C)=O)C=C1O2
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at +4°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

CFDA is a popular, sensitive, fluorescent substrate for measuring esterase activity in live cells. It is often used in cell viability assays and "Live-Dead" assay systems, especially automated cell viability assays. The cleavage product produced upon enzymatic or chemical hydrolysis of the acetate group(s) is carboxyfluorescein which is well-retained inside live cells, while the substrate CFDA is membrane permeant.

Product References

(1) C. Thrane et al.; J. Microbiol.l Meth. 28(1), 35 (1997) | (2) G. Liminga et al.; Anti-Cancer Drugs 6(4), 578 (1995) | (3) L.S. DeClerck et al.; J. Immun. Meth. 172(1), 115 (1994)

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