4-Di-2-ASP

CHF 154.00
In stock
CDX-D0012-G0011 gCHF 154.00
CDX-D0012-G0055 gCHF 583.00
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Product Details
Synonyms 4-(4-Diethylaminostyryl)-1-methylpyridinium iodide; DiASP
Product Type Chemical
Properties
Formula

C18H23IN2

MW 394.29
CAS 105802-46-8
Source/Host Chemicals Synthetic.
Purity Chemicals ≥97% (NMR)
Appearance Dark red crystalline powder.
Solubility Soluble in DMSO, DMF or chloroform.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key WIPKWLIHFGTFQV-UHFFFAOYSA-M
Smiles [I-].CCN(CC)C1=CC=C(\C=C\C2=CC=[N+](C)C=C2)C=C1
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at +4°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF

Some cationic mitochondrial dyes such as 4-Di-1-ASP and 4-Di-2-ASP stain presynaptic nerve terminals independent of neuronal activity. The photostable 4-Di-2-ASP dye, which is nontoxic to cells, has been employed to stain living nerve terminals in rabbit corneal epithelium, in rat epidermis and at mouse, snake and frog neuromuscular junctions, as well as to visualize the innervation of the human choroid and whole mounts of the gastrointestinal tract. Methods for using 4-Di-2-ASP to image neuronal cells in live animals have been described (Ex/Em = 488/607 nm).

Product References

(1) C. Seebacher et al.; Adv. Mat. 13(18), 1374 (2001) | (2) R.S. Wilkinson et al.; J. Neurosci. 14, 3319 (1994) | (3) L. Chen et al.; J. Neurosci. 14, 796 (1994) | (4) M.B. MacIver et al.; J. Neurosci. 13, 4511 (1993) | (5) A.A. Herrera et al.; J. Neurocytol. 19, 67 (1990) | (6) C.A. Nurse et al.; Cell Tissue Res. 255, 125 (1989)

Thyroid hormone coordinates developmental trajectories but does not underlie developmental truncation in danionins: Y. Hu, et al.; Dev. Dyn. 248, 1144 (2019) 

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