IL-10 (human) (rec.) (His)

CHF 270.00
In stock
CHI-HR-20010-C01010 µgCHF 270.00
CHI-HR-20010-C05050 µgCHF 945.00
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Product Details
Synonyms Interleukin-10; Cytokine Synthesis Inhibitory Factor; CSIF
Product Type Protein
Properties
Source/Host E. coli
Sequence Human IL-10 (aa 19-178) is fused at the N-terminus to a His-tag.
Crossreactivity Human
Purity ≥95% (SDS-PAGE)
Endotoxin Content <0.1EU/μg protein (LAL test; Lonza).
Reconstitution Reconstituted in sterile H2O not less than 100μg/ml, which can then be further diluted in other aqueous solutions.
Formulation Lyophilized from 0.2μm-filtered solution in PBS (pH 7.4).
Other Product Data NCBI reference NP_000563.1: IL-10 (human)
Declaration Manufactured by Chimerigen.
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability Stable for at least 1 year after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells and monocytes/macrophages. Several studies have suggested the potential application of IL-10 as an anti-inflammatory agent in the treatment of septic shock and as an immunosuppressive agent in certain T cell mediated autoimmune diseases.

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