CX-6258

CHF 227.00
In stock
SYN-1182-M0011 mgCHF 227.00
SYN-1182-M0055 mgCHF 383.00
SYN-1182-M01010 mgCHF 551.00
SYN-1182-M05050 mgCHF 1'646.00
SYN-1182-M100100 mgCHF 2'568.00
 
More Information
Product Details
Synonyms CX6258
Product Type Chemical
Properties
Formula C26H24ClN3O3
MW 461.9
CAS 1202916-90-2
Purity Chemicals ≥95%
Appearance Solid.
Solubility Soluble in DMSO.
Declaration Manufactured by SynKinase.
Other Product Data Target: PKC - PKCα | Kinase Group: STE | Substrate: Serine-Threonine

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key KGBPLKOPSFDBOX-CJLVFECKSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
CX6258 is a potent inhibitor of Pim-1, Pim-2 and Pim-3 with IC(50) values of 5, 25 and 16nM, respectively.
Product References
  1. CX-4945, an orally bioavailable selective inhibitor of protein kinase CK2, inhibits prosurvival and angiogenic signaling and exhibits antitumor efficacy: A. Siddiqui-Jain, et al.; Cancer Res. 70, 10288 (2010)
  2. Discovery of CX-6258. A Potent, Selective, and Orally Efficacious pan-Pim Kinases Inhibitor: M. Haddach, et al.; ACS Med. Chem. Lett. 3, 135 (2011)
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