NLRP3 Inflammasome Human Reagents Starter Set

Each antibody in the NLRP3 Inflammasome Human Reagents Starter Set has been thoroughly validated in KO experimental setup and detects endogenous levels of its target protein.

Both chemicals LPS and Nigericin in the NLRP3 Inflammasome Human Reagents Starter Set are required for priming (Signal 1) and activation (Signal 2) of the NLRP3  inflammasome, respectively.

• AG-20B-0014      anti-NLRP3/NALP3, mAb (Cryo-2) - 25 µg
• AG-20B-0048      anti-Caspase-1 (p20) (human), mAb (Bally-1) - 25 µg
• AG-25B-0006      anti-Asc, pAb (AL177) - 25 µg
• IAX-100-007        LPS from E. coli R515 (Re) TLRpure Sterile Solution - 500 µg
• AG-CN2-0020     Nigericin . sodium salt - 5 mg

Note: All antibodies are supplied at a concentration of 0.5 mg/ml in PBS, containing a preservative. Nigericin is provided as solid powder. These components are provided in a box and can be stored for ≥12 months after receipt at -20°C.The LPS is provided in a Ready-to-Use solution in a separate container together with the box and should be stored at 4°C after receipt. Freeze/thaw cycles for LPS should be avoided.