AdipoGen Life Sciences

NG 011

CHF 150.00
In stock
AG-CN2-0178-M0011 mgCHF 150.00
AG-CN2-0178-M0055 mgCHF 600.00
More Information
Product Details
Synonyms NG-011; BK223B; 15G256α1
Product Type Chemical
Properties
Formula

C32H38O15

MW 662.7
CAS 141731-75-1
Source/Host Chemicals Isolated from Penicillium sp.
Purity Chemicals ≥95% (HPLC)
Appearance Off-white solid.
Solubility Soluble in methanol, ethanol or DMSO (all 1mg/ml).
InChi Key MRSORNRSXAQNPV-VVIQKPQNSA-N
Smiles OC(C=C1O)=CC(C[C@@H](C)OC(C[C@@H](C)O2)=O)=C1C(O[C@H](C)CC(O[C@@H](O)CC(O[C@H](C)CC(C=C(O)C=C3O)=C3C2=O)=O)=O)=O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
Description
  • Antibiotic. Mycotoxin. Very weak cytotoxic activity.
  • Antifungal. Inhibits cell wall biosynthesis.
  • Nerve growth factor (NGF) potentiator.
Product References
  1. NG 011 and NG 012, novel potentiators of nerve growth factor. I. Taxonomy, isolation, and physico-chemical and biological properties: M. Ito, et al.; J. Antibiot. 45, 1559 (1992)
  2. NG 011 and NG 012, novel potentiators of nerve growth factor. II. The structure determination of NG-011 and NG-012: M. Ito, et al.; J. Antibiot. 45, 1566 (1992)
  3. Antifungal macrocyclic polylactones from Penicillium verruculosum: J. Breinholt, et al.; J. Antibiot. 46, 1101 (1993)
  4. Isolation and identification of antifungal polyesters from the marine fungus Hypoxylon oceanicum LL-15G256: G. Schlingmann, et al.; Tetrahedron 58, 6825 (2002)
  5. Biomimetic Synthesis of Resorcylate Natural Products Utilizing Late Stage Aromatization: Concise Total Syntheses of the Marine Antifungal Agents 15G256ι and 15G256β: I. Navarro, et al.; JACS 130, 10293 (2008)
  6. New Cytotoxic Metabolites from the Marine-Derived Fungus Penicillium sp. ZLN29: H. Gao, et al.; Helv. Chim. Acta 96, 514 (2013)
  7. New polyesters from Talaromyces flavus: J.-W. He, et al.; Tetrahedron 70, 4425 (2014)
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