Cookie Policy: This site uses cookies to improve your experience. You can find out more about our use of cookies in our Privacy Policy. By continuing to browse this site you agree to our use of cookies.
Ancell
anti-CD257 [BAFF] (human), mAb (ANC2H3) (preservative free)
306
CHF
CHF 306.00
In stock
ANC-266-820100 µgCHF 306.00
| Product Details | |
|---|---|
| Synonyms | BAFF; Blys; TALL-1; B Cell Activating Factor; Tumor Necrosis Factor Ligand Superfamily Member 13B; TNFSF13B |
| Product Type | Monoclonal Antibody |
| Properties | |
| Clone | ANC2H3 |
| Isotype | Mouse IgG1κ |
| Immunogen/Antigen | Recombinant soluble human CD257(BAFF). |
| Label/Conjugates | Preservative Free |
| Application |
ELISA |
| Crossreactivity | Human |
| Formulation | 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl |
| Isotype Negative Control | |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet |
| Declaration | Manufactured by Ancell Corporation. |
| Shipping and Handling | |
| Shipping | BLUE ICE |
| Short Term Storage | +4°C |
| Long Term Storage | +4°C |
| Handling Advice | Avoid freeze/thaw cycles. |
| Use/Stability | Stable for at least 1 year after receipt when stored at +4°C. |
| Documents | |
| MSDS | Inquire |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
Description
BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren’s syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).
Related Products
