anti-FOXP3 (human), mAb (ANCFX2D7) (Biotin)

CHF 352.00
In stock
ANC-333-030100 µgCHF 352.00
More Information
Product Details
Synonyms Forkhead Box Protein P3; Scurfin; IPEX, JM2
Product Type Monoclonal Antibody
Properties
Clone ANCFX2D7
Isotype Mouse IgG1κ
Immunogen/Antigen Recombinant human FOXP3.
Label/Conjugates Biotin
Application

ELISA
Flow Cytometry

Crossreactivity Human
Specificity

Recognizes human FOXP3.

Purity ≥95% (SDS-PAGE)
Purity Detail Protein A-affinity purified.
Formulation 50mM Sodium phosphate pH7.5, 100mM Potassium chloride, 150mM NaCl, 5% glycerol, 0.2%BSA, 0.04% sodium azide (as preservative).
Isotype Negative Control

Mouse IgG1 Isotype Control (Biotin)

Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Declaration Manufactured by Ancell Corporation.
Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage +4°C
Handling Advice Avoid freeze/thaw cycles.
Use/Stability Stable for at least 1 year after receipt when stored at +4°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

FOXP3 is involved in immune system responses. It functions as the master regulator in the development and function of regulatory T cells. FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX); also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema.

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