CD257 [BAFF] (trn) (human)-muCD8 Fusion Protein (preservative free)
460 CHF CHF 460.00
ANC-525-82025 µgCHF 460.00
|Synonyms||BAFF; Blys; TALL-1; B Cell Activating Factor; Tumor Necrosis Factor Ligand Superfamily Member 13B; TNFSF13B|
|Formulation||50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl|
|Other Product Data||
Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
|Declaration||Manufactured by Ancell Corporation.|
|Shipping and Handling|
|Short Term Storage||+4°C|
|Long Term Storage||+4°C|
|Handling Advice||Avoid freeze/thaw cycles.|
|Use/Stability||Stable for at least 6 months after receipt when stored at +4°C.|
|Product Specification Sheet|
BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren’s syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).