Fluo-3 AM

CHF 264.00
In stock
CDX-F0033-M0011 mgCHF 264.00
CDX-F0033-M01010 mgCHF 2'144.00
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Product Details
Synonyms Fluo-3 AM
Product Type Chemical
Formula C51H50Cl2N2O23
MW 1129.85
CAS 121714-22-5
Source/Host Chemicals Synthetic.
Purity Chemicals ≥90% (TLC)
Appearance Dark red powder.
Solubility Soluble in DMSO.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

Shipping and Handling
Shipping BLUE ICE
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF

Ca2+-indicator fluo-3 for use with visible-light excitation sources in flow cytometry and confocal laser-scanning microscopy. Since about 1996, fluo-3 has also been extensively used in cell-based high-throughput screening assays for drug discovery. Fluo-3 AM is essentially nonfluorescent until it is hydrolyzed intracellularly and/or in the presence of Ca2+. The green-fluorescent emission (~525 nm) of Ca2+-bound fluo-3 is conventionally detected using optical filter sets designed for fluorescein (FITC). As prepared by Minta, Kao and Tsien, fluo-3 was originally reported to undergo an ~40-fold increase in fluorescence upon binding Ca2+.

Product References

(1) T. Toyofuku et al.; Geochem., Geophys., Geosyst. 9(5) | (2008) | (2) D.M. Plank et al.; Meth. Cell Sc. 25(3-4), 123 (2004) | (3) P. Vandenberghe et al.; J. Immun.Meth. 127, 197 (1990) | (4) J.P.Y. Kao et al.; J. Biol. Chem. 264, 8179 (1989)

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