Chemodex

Fluo-3 AM

As low as CHF 264.00

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CDX-F0033-M0011 mgCHF 264.00

CDX-F0033-M01010 mgCHF 2’144.00

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Product Details
Synonyms	Fluo-3 AM
Product Type	Chemical
Properties
Formula	C₅₁H₅₀Cl₂N₂O₂₃
MW	1129.85
CAS	121714-22-5
Source/Host Chemicals	Synthetic.
Purity Chemicals	≥90% (TLC)
Appearance	Dark red powder.
Solubility	Soluble in DMSO.
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	PTPUOMXKXCCSEN-UHFFFAOYSA-N
Smiles	CC(=O)OCOC(=O)CN(CC(=O)OCOC(C)=O)C1=CC=C(C=C1OCCOC1=C(C=CC(C)=C1)N(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)C1=C2C=C(Cl)C(=O)C=C2OC2=CC(OCOC(C)=O)=C(Cl)C=C12
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

Ca2+-indicator fluo-3 for use with visible-light excitation sources in flow cytometry and confocal laser-scanning microscopy. Since about 1996, fluo-3 has also been extensively used in cell-based high-throughput screening assays for drug discovery. Fluo-3 AM is essentially nonfluorescent until it is hydrolyzed intracellularly and/or in the presence of Ca2+. The green-fluorescent emission (~525 nm) of Ca2+-bound fluo-3 is conventionally detected using optical filter sets designed for fluorescein (FITC). As prepared by Minta, Kao and Tsien, fluo-3 was originally reported to undergo an ~40-fold increase in fluorescence upon binding Ca2+.

Product References

(1) T. Toyofuku et al.; Geochem., Geophys., Geosyst. 9(5) | (2008) | (2) D.M. Plank et al.; Meth. Cell Sc. 25(3-4), 123 (2004) | (3) P. Vandenberghe et al.; J. Immun.Meth. 127, 197 (1990) | (4) J.P.Y. Kao et al.; J. Biol. Chem. 264, 8179 (1989)

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