Chemodex

N-(3-Hydroxydecanoyl)-L-homoserine lactone

CHF 204.00

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CDX-H0086-M0055 mgCHF 204.00

CDX-H0086-M02525 mgCHF 815.00

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Product Details
Synonyms	OH-C10-HSL; 3-Hydroxy-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-decanamide
Product Type	Chemical
Properties
Formula	C₁₄H₂₅NO₄
MW	271.35
CAS	192883-12-8
Source/Host Chemicals	Synthetic.
Purity Chemicals	≥97% (NMR)
Appearance	White to off-white powder.
Solubility	Soluble in DMSO, DMF (both 20mg/ml) or acetonitrile.
Identity	Determined by ¹H-NMR.
Declaration	Manufactured by Chemodex.
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
InChi Key	DOICJCCMIBBSOO-KIYNQFGBSA-N
Smiles	O=C1[C@@H](NC(CC(O)CCCCCCC)=O)CCO1
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Protect from light and moisture.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

N-3-hydroxydecanoyl-L-homoserine lactone is a small diffusible signaling molecule secreted by various bacteria and involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. This lactone is produced via lactonolysis from 3-oxodecanoyl-homoserine lactone, altering quorum sensing or contributing to quorum quenching. The applications of this molecule include regulation of virulence and exoproteases.

Product References

(1) P. Lumjiaktase, et al.; Microbiol. 152, 3651 (2006) | (2) A. Fekete, et al.; Anal. Bioanal. Chem. 387, 455 (2007) | (3) X. Chen, et al.; Anal. Bioanal. Chem. 398, 2655 (2010) | (4) K.G. Chan, et al.; BMC Microbiol. 11, 1 (2011) | (5) C.W. Ha, et al.: Mol. Cells 33, 53 (2012)

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