RevMab

anti-CD155 [PVR] (human), Rabbit Monoclonal (RM514)

CHF 468.00

In stock

REV-31-1406-00-R100100 µlCHF 468.00

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Figure 1: Immunohistochemical staining of formalin-fixed and paraffin-embedded human breast cancer tissue sections using anti-CD155 Rabbit Monoclonal Antibody (Clone RM514) at 1:500 dilution for 1 hr at room temperature.

Specifications / Handling

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Product Details
Synonyms	PVR; Poliovirus receptor; Nectin-like protein 5; NECL-5
Product Type	Recombinant Antibody
Properties
Clone	RM514
Isotype	Rabbit IgG
Source/Host	Rabbit
Immunogen/Antigen	A peptide corresponding to residues near the C-terminus of human CD155.
Application	Immunohistochemistry (IHC): 1:100-1:500 Western Blot (WB): 1:500-1:1000
Crossreactivity	Human
Specificity	This antibody reacts to human CD155 (PVR; Poliovirus receptor; NECL-5).
Purity	Protein A purified.
Purity Detail	Protein A affinity purified from an animal origin-free culture supernatant.
Formulation	Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Isotype Negative Control	Rabbit IgG
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
Accession Number	P15151
Declaration	Manufactured by RevMab Biosciences.
Shipping and Handling
Shipping	BLUE ICE
Long Term Storage	-20°C
Handling Advice	Avoid freeze/thaw cycles.
Use/Stability	Stable for at least 1 year after receipt when stored at -20°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

Human CD155 (Polio Virus Receptor, PVR, Necl-5) is a 70kd type I Ig superfamily molecule. It is involved in formation of intracellular junctions between epithelial cells. Its ligands include CD226 (DNAM-1), and CD96 (TACTILE). CD155 expression by tumor has been shown to be upregulated by nitric oxide. A soluble version of CD155 has been shown to exist. High CD155 expression has recently been exploited to use engineered poliovirus to treat glioblastoma.

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