Ancell

anti-CD257 [BAFF] (human), mAb (ANC2H3) (R-PE)

CHF 455.00

In stock

ANC-266-050120 testsCHF 455.00

More Information
Product Details
Synonyms	BAFF; Blys; TALL-1; B Cell Activating Factor; Tumor Necrosis Factor Ligand Superfamily Member 13B; TNFSF13B
Product Type	Monoclonal Antibody
Properties
Clone	ANC2H3
Isotype	Mouse IgG1κ
Immunogen/Antigen	Recombinant soluble human CD257(BAFF).
Label/Conjugates	FITC
Application	ELISA Flow Cytometry Functional Application: Blocking
Crossreactivity	Human
Formulation	50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative).
Isotype Negative Control	Mouse IgG1 Isotype Control (R-PE)
Other Product Data	Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet.
Declaration	Manufactured by Ancell Corporation.
Shipping and Handling
Shipping	BLUE ICE
Short Term Storage	+4°C
Long Term Storage	+4°C
Handling Advice	Do not freeze. Protect from light.
Use/Stability	Stable for at least 1 year after receipt when stored at +4°C.
Documents
MSDS	Inquire
Product Specification Sheet
Datasheet	Download PDF

Product-specific References

Description

BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren’s syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).

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