Ecdysterone

CHF 87.00
In stock
CDX-E0225-M0055 mgCHF 87.00
CDX-E0225-M02525 mgCHF 260.00
More Information
Product Details
Synonyms 20-Hydroxyecdysone; β-Ecdysone; 2β,3β,14α,20β,22,25-Hexahydroxy-7-cholesten-6-one; Insect moulting hormone; Polypodine A
Product Type Chemical
Properties
Formula

C27H44O7

MW 480.63
CAS 5289-74-7
Source/Host Chemicals Synthetic
Purity Chemicals ≥97% (HPLC)
Appearance White to off-white powder.
Solubility Soluble in methanol (20mg/ml), DMSO or ethanol.
Identity Determined by 1H-NMR.
Declaration Manufactured by Chemodex.
Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.

InChi Key NKDFYOWSKOHCCO-MQMWGCQISA-N
Smiles [H][C@@]1(CC[C@@]2(O)C3=CC(=O)[C@]4([H])C[C@@H](O)[C@@H](O)C[C@]4(C)C3CC[C@]12C)[C@@](C)(O)[C@H](O)CCC(C)(C)O
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light and moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Inquire
Product Specification Sheet
Datasheet Download PDF

A member of the ecdysteroid family. Ecdysone receptor (EcR) agonist. More potent than ecdysone. Induces the expression of genes coding for proteins that the larva requires, and it causes chromosome puffs (sites of high expression) to form in polytene chromosomes. Plays a key role in insect development, cell proliferaton, growth and apoptosis by controlling gene expression involved in moulting and metamorphosis. It acts through a heterodimeric receptor comprising the ecdysone receptor and the ultraspiracle proteins (USP). Used for controlled gene expression in scientific research, agriculture and medicine. Used for the development of selective insect growth regulators for use as environmentally benign insecticides. Shows biological effects on mammalian species, including antiepileptic, antidiabetic, antiobesity, ROS-inhibiting activity.ht produces vitamin D3. UV/Vis: λmax 271, 282, 293nm.

Product References

(1) F. Engelmann; Science 174, 1041 (1971) | (2) S. Tsujiyama, et al.;  Jpn. J. Pharmacol. 68, 133 (1995) | (3) E.H. Baehrecke, et al.; Arch. Insect Biochem. Physiol. 33, 231 (1996) | (4) R. Hanaya, et al.; Jpn. J. Pharmacol. 74, 331 (1997) | (5) L.M. Riddiford, et al.; Vitam. Horm. 60, 1 (2000) | (6) C.S Thummel; Insect Biochem. Mol. Biol. 32, 113 (2002) | (7) L.D. Graham; Expert Opin. Biol. Ther. 2, 525 (2002) | (8) P.  Kizelsztein, et al.; Am. J. Physiol. Endocrinol. Metab. 296, E433 (2009) | (9) J. Hu, et al.; J. Cell Biochem. 111, 1512 (2010)

© 2017 Adipogen Life Sciences. Pictures: © 2012 Martin Oeggerli. All Rights Reserved.