AdipoGen Life Sciences

BE-31405

CHF 350.00

In stock

AG-CN2-0302-M0011 mgCHF 350.00

More Information
Product Details
Product Type	Chemical
Properties
Formula	C₂₈H₃₆O₁₀
MW	532.6
CAS	158054-02-5
Source/Host Chemicals	Isolated from Penicillum minioluyeum.
Purity Chemicals	≥98% (HPLC)
Appearance	White to off-white powder.
Solubility	Soluble in DMSO.
Identity	Determined by ¹H-NMR and MS.
InChi Key	ULHRLJDDVCQHQE-IXWUSAGWSA-N
Smiles	C[C@H](CC1)[C@]2([H])[C@]1([H])[C@]3(C=O)[C@](C(C(C)C)=C4)(C(O)=O)[C@]([C@@H]4C3)(CO[C@@]5(O6)O[C@]7([H])[C@@]6([H])O[C@H]([C@@H]5O)[C@H]7OC(C)=O)C2
Shipping and Handling
Shipping	AMBIENT
Short Term Storage	+4°C
Long Term Storage	-20°C
Handling Advice	Keep cool and dry. Protect from light. Protect from light when in solution.
Use/Stability	Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS	Download PDF
Product Specification Sheet
Datasheet	Download PDF

Description

Broad spectrum antifungal agent compared to sordarin. Shows growth inhibitory activity against pathogenic fungal strains such as Candida albicans, C. glabrata and Cryptococcus neoformans.
Inhibits the protein synthesis in C. albicans, but not mammalian cells, most probably through elongation factor inhibition.

Product References

BE-31405, a new antifungal antibiotic produced by Penicillium minioluteum. I. Description of producing organism, fermentation, isolation, physico-chemical and biological properties: H. Okada, et al.; J. Antibiot. 51, 1081 (1998)
Induced production of BE-31405 by co-culturing of Talaromyces siamensis FKA-61 with a variety of fungal strains: K. Nonaka, et al.; J. Antibiot. 68, 573 (2015)

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