Rifamycin PR-3

CHF 120.00
In stock
AG-CN2-0335-M01010 mgCHF 120.00
AG-CN2-0335-M05050 mgCHF 480.00
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Product Details
Synonyms 3'-​(Methoxycarbonyl)​-​1',​2'-​dimethyl-rifamycin II; NCI 143-458; NCI 143458
Product Type Chemical


MW 806.9
CAS 21288-98-2
Source/Host Chemicals Semisynthetic.
Purity Chemicals ≥94% (HPLC)
Appearance Yellow to orange powder.
Solubility Soluble in DMSO, aqueous acetonitrile or ethanol.
Identity Determined by 1H-NMR and MS.
Smiles OC1=C(NC(/C(C)=C\C=C\[C@H](C)[C@H](O)[C@@H](C)[C@H]([C@@H](C)[C@@H]([C@H](C)[C@H](/C=C/O2)OC)OC(C)=O)O)=O)C3=C(N(C)C(C)=C3C(OC)=O)C4=C5C(O[C@@]2(C)C5=O)=C(C)C(O)=C41
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Protect from light.
Protect from light when in solution.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
  • Ansamycin antibiotic.
  • Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP).
  • Effective against mycobacteria and therefore used in research of tuberculosis, leprosy and Mycobacterium avium complex (MAC) infections.
Product References
  1. Rifamycin antibiotics: inhibitors of Rauscher murine leukemia virus reverse transcriptase and of purified DNA polymerases from human normal and leukemic lymphoblasts: S.S. Yang, et al.; J. Natl. Cancer Inst. 49, 7 (1972)
  2. Rifamycin Derivatives Strongly Inhibiting RNA>DNA Polymerase (Reverse Transcriptase) of Murine Sarcoma Viruses: C. Gurgo, et al.; J. Natl. Cancer Inst. 49, 61 (1972)
  3. Reverse transcriptase, RNA tumour virus transformation and derivatives of rifamycin SV: R.C. Ting, et al.; Nat. New Biol. 236, 163 (1972)
  4. Interaction between murine type-C virus RNA-directed DNA polymerases and rifamycin derivatives: A.M. Wu & R.C. Gallo; Biochim. Biophys. Acta 340, 419 (1974)
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