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SouthBayBio
KTSAVLQ-Rhodamine110-γ-Glu
Product Details | |
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Synonyms | Lys-Tyr-Ser-Ala-Val-Leu-Glu-Rhodamine110-γ-Glu |
Product Type | Chemical |
Properties | |
MW | 1187.3 |
Sequence |
Lys-Tyr-Ser-Ala-Val-Leu-Glu-Rhodamine110-γ-Glu |
Purity Chemicals | ≥99% (HPLC) |
Appearance | Lyophilized powder. |
Solubility | Soluble in physiological aqueous buffer. |
Declaration | Manufactured by South Bay Bio. |
Other Product Data |
Click here for a Typical Lot-specific Product Datasheet from the Original Manufacturer |
Shipping and Handling | |
Shipping | BLUE ICE |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice |
Avoid freeze/thaw cycles. Protect from light. Protect from light when in solution. |
Use/Stability | Stable for at least 1 year after receipt when stored at -20°C. |
Documents | |
MSDS | Inquire |
Product Specification Sheet | |
Datasheet | Download PDF |
KTSAVLQ-Rhodamine110-y-Glu (Lys-Tyr-SerAla-Val-Leu-Glu-Rh110-y-Glu) is a Rhodamine110 labeled fluorogenic peptidyl substrate that can be hydrolyzed by 3CLpro (Mpro) (#SBB-DE0129) a chemotrypsin-like protease, cleaving between the glutamine and the Rhodamine110 fluorophore. Prior hydrolysis, the Rhodamine110 moiety is quenched resulting in a very low background. This substrate is ideal for activity determination of 3CLpro and suitable for HTS or pilot screens in search for potential inhibitors due to its red-shifted fluorescence compared to AMC or Dabcyl/Edans substrates. This results in less interference with potential inhibitors in screeing campaigns. Ex/Em=485nm/535nm (recommended).