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Innovative Research Reagents for Inflammation & Immune Responses
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Latest Product Highlights ArchiveNew Highly Specific & Sensitive Insulin ELISA Kit
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News & Press ReleasesAbcalis and AdipoGen Life Sciences Partner on Distributing Animal-free Recombinant Monoclonal and Multiclonal Antibodies on the Life Science Research Market BAFF and APRIL have Opposite Functions in Inflammation during Parturition A recent study in Cell Reports shows the BAFF/APRIL axis is activated in inflammation-induced preterm birth (PTB). Macrophages produce BAFF at the maternal-fetal interface and BAFF enhances inflammatory responsiveness and increases susceptibility to PTB. APRIL has the opposite function in PTB decreasing inflammation. Therefore, the new roles of BAFF or APRIL in parturition open new therapeutic possibilities for mitigating the risk of inflammation-induced PTB. |
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