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Innovative Research Reagents for Inflammation & Immune Responses
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Latest Product Highlights ArchiveCreate a BAFF KO phenotype in Mice by One Injection
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News & Press ReleasesAbcalis and AdipoGen Life Sciences Partner on Distributing Animal-free Recombinant Monoclonal and Multiclonal Antibodies on the Life Science Research Market FMRP Regulates Tumor Growth by Activating T Regulatory Cells via Interleukin-33 A recent study published in Science reports that FMRP hyperexpressing cancer cells produce interleukin-33 (IL-33), as well as the tumor-secreted protein S (PROS1) ligand and exosomes. FMRP acts as a regulator of a network of genes (IL-33, PROS1) and cells (Treg, M2 macrophages and potentially additional classes of myeloid cells) in the tumor microenvironment that helps cancer cells to evade immune destruction. |
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